Journal: Nature and Science of Sleep
Article Title: Increased Gray Matter Density and Functional Connectivity of the Pons in Restless Legs Syndrome
doi: 10.2147/NSS.S239852
Figure Lengend Snippet: Multivariate pattern analysis using support vector machine (SVM) was applied to provide provisional evidence to determine whether identified neural indices might serve to distinguish RLS patients from NC. ( A ) We used a leave-one-out cross-validation strategy to estimate the generalization ability of our classifier. Features of gray matter density in pons_2, and functional connectivity between pons_2 and SMA were used. The classification accuracy, specificity, and precision were showed. ( B ) The receiver operating characteristic (ROC) curve. AUC, area under the curve.
Article Snippet: To clarify whether the identified abnormal features might have potential power for diagnosing RLS, we performed a linear SVM approach within LIBSVM in MATLAB.
Techniques: Plasmid Preparation, Biomarker Discovery, Functional Assay